Article
Matrix metalloproteinase 3 and 9 as genetic biomarkers for the occurrence of cardiovascular complications in coronary artery disease: a prospective cohort study.
Molecular biology reports - 1 Oct 2022
Guizani Imen, Zidi Wiem, Zayani Yosra, Nesrine Fourti, Douik Hayet, Sanhaji Haifa, Mourali Mohamed Sami, Feki Moncef, Allal-Elasmi Monia
Abstract excerpt
BACKGROUND: Matrix metalloproteinases (MMPs) are widely expressed in atherosclerosis lesions. The disequilibrium of MMPs driving to an overexpression or a lack of its level can be influenced by genetic variations. MMP-3 and MMP-9 may be affected by specific polymorphisms like - 1612 5 A/6A and the - 1562 C/T respectively. We aim in the present study to investigate prospectively the association between the - 1612...
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