Article
Prognostic Value of Different Allelic Polymorphism of Aldosterone Synthase Receptor in a Congestive Heart Failure European Continental Ancestry Population.
Archives of medical research - 1 Feb 2017
Feola Mauro, Monteverde Martino, Vivenza Daniela, Testa Marzia, Leto Laura, Astesana Valentina, Mussapi Francesco, Vado Antonello, Merlano Marco, Lo Nigro Cristiana
Abstract excerpt
Aldosterone synthase (CYP11B2) is as an 9-exon gene on chromosome 8q22 and exists as a common single nucleotide polymorphism C-T transition for position -344. The aim of this study was to assess the -344T/C polymorphism of the aldosterone synthase promoter in a European continental ancestry congestive heart failure (CHF) population. METHODS: Patients discharged after an acute decompensation were enrolled and...
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