Article
T allele of -344 C/T polymorphism in aldosterone synthase gene is not associated with resistant hypertension.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Feb 2009
Lacchini Riccardo, Sabha Maricene, Coeli Fernanda B, Favero Fabrício F, Yugar-Toledo Juan, Izidoro-Toledo Tatiane C, Sandrim Valéria C, Tanus-Santos José E, de Mello Maricilda P, Moreno Heitor
Abstract excerpt
Resistant hypertension (RH) is the maintenance of elevated blood pressure concurrent with the use of three different anti-hypertensive drugs, one of which is a diuretic. The Renin-Angiotensin-Aldosterone System plays a major role in volume-dependent hypertension. Therefore, its components are interesting targets for genetic association studies. This work focused on the -344 C/T polymorphism in the CYP11b2 gene,...
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