Article
Relationship between -344T/C polymorphism in the aldosterone synthase gene and atrial fibrillation in patients with essential hypertension.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2011
Sun Xiaojian, Yang Jun, Hou Xiaofei, Li Jun, Shi Yu, Jing Yanyan
Abstract excerpt
INTRODUCTION: Aldosterone plays an important role in the pathogenesis of non-familial atrial fibrillation (AF). We tested the hypothesis that the -344T/C polymorphism in the aldosterone synthase gene may be associated with non-familial AF in Chinese patients with hypertension. MATERIALS AND METHODS: We performed a 1:1 paired case-control study in 310 cases of hypertension with AF and same number matched controls....
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