Association of aldosterone synthase polymorphism (CYP11B2 -344T>C) and genetic ancestry with atrial fibrillation and serum aldosterone in African Americans with heart failure.

doi:10.1371/journal.pone.0071268

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association of aldosterone synthase polymorphism (CYP11B2 -344T>C) and genetic ancestry with atrial fibrillation and serum aldosterone in African Americans with heart failure.

PloS one - 1 Jan 2013

Bress Adam, Han Jin, Patel Shitalben R, Desai Ankit A, Mansour Ibrahim, Groo Vicki, Progar Kristin, Shah Ebony, Stamos Thomas D, Wing Coady, Garcia Joe G N, Kittles Rick, Cavallari Larisa H

Abstract excerpt

The objective of this study was to examine the extent to which aldosterone synthase genotype (CYP11B2) and genetic ancestry correlate with atrial fibrillation (AF) and serum aldosterone in African Americans with heart failure. Clinical data, echocardiographic measurements, and a genetic sample for determination of CYP11B2 -344T>C (rs1799998) genotype and genetic ancestry were collected from 194 self-reported...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aldosterone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Atrial Fibrillation

Share to Black or African American

Share to Cytochrome P-450 CYP11B2

Share to Gene Frequency

Share to Genetic Association Studies

Share to Heart Failure

Share to White People

Source

Open in PubMed Open full text

Identifiers

PMID: 23936266
DOI: 10.1371/journal.pone.0071268
PMCID: PMC3728110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of aldosterone synthase polymorphism (CYP11B2 -344T>C) and genetic ancestry with atrial fibrillation and serum aldosterone in African Americans with heart failure.PMID 23936266Read ↗

Aldosterone synthase promoter polymorphism predicts outcome in African Americans with heart failure: results from the A-HeFT Trial.Semantic proximity Read ↗

Usefulness of the aldosterone synthase gene polymorphism C-344-T to predict cardiac remodeling in African-Americans versus non-African-Americans with chronic systolic heart failure.Semantic proximity Read ↗

Aldosterone synthase gene polymorphism as a determinant of atrial fibrillation in patients with heart failure.Semantic proximity Read ↗

CYP11B2 T-344C gene polymorphism and atrial fibrillation: a meta-analysis of 2,758 subjects.Semantic proximity Read ↗

Prognostic Value of Different Allelic Polymorphism of Aldosterone Synthase Receptor in a Congestive Heart Failure European Continental Ancestry Population.Semantic proximity Read ↗

Aldosterone synthase gene (CYP11B2) C-344T polymorphism, plasma aldosterone, renin activity and blood pressure in a multi-ethnic population.Semantic proximity Read ↗

Characterization of genome-wide association-identified variants for atrial fibrillation in African Americans.Semantic proximity Read ↗

African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women's Health Initiative.Semantic proximity Read ↗

Race, common genetic variation, and therapeutic response disparities in heart failure.Semantic proximity Read ↗

Genetic Ancestry and Risk of Atrial Fibrillation in Individuals of Black Ethnicity in the UK BiobankSemantic proximity Read ↗

Aldosterone Synthase Promoter Polymorphism and Cardiovascular Phenotypes in a Large, Multiethnic Population-Based Study.Semantic proximity Read ↗

Pharmacogenetics of heart failure: evidence, opportunities, and challenges for cardiovascular pharmacogenomics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.