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Activating killer cell immunoglobulin‐like receptors: Detection, function and therapeutic use

22 Nov 2019

Abstract excerpt

Killer cell immunoglobulin-like receptors (KIRs) have a central role in the control of natural killer (NK) cell function. The functions of the activating KIRs, as compared to those of the inhibitory KIR, have been more difficult to define due to difficulties in antibody-mediated identification and their apparent low affinities for HLA class I. Immunogenetic studies have shown associations of activating KIRs with...

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PMID: 31755661
DOI: 10.1111/iji.12461

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