Article

Peptide:MHC dependent activation of natural killer cells through KIR2DS2 generates anti-tumor responses

2020-04-15

Abstract excerpt

Natural killer (NK) cells are key components of the immune response to viral infections and cancer. Their functions are controlled by activating and inhibitory killer-cell immunoglobulin-like receptors (KIR) which have MHC class I ligands. KIR2DS2 is an activating KIR, that binds conserved viral peptides in the context of HLA-C and has been associated with protective responses to both cancer and viral infections....

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Literature Corpus work: ed95efd0-7d5e-546e-9e27-854da7c1ef9a
DOI: 10.1101/2020.04.15.042077

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