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Article

Exploring the Causal Pathway From Telomere Length to Coronary Heart Disease: A Network Mendelian Randomization Study.

Circulation research - 21 Jul 2017

Zhan Yiqiang, Karlsson Ida K, Karlsson Robert, Tillander Annika, Reynolds Chandra A, Pedersen Nancy L, Hägg Sara

Abstract excerpt

RATIONALE: Observational studies have found shorter leukocyte telomere length (TL) to be a risk factor for coronary heart disease (CHD), and recently the association was suggested to be causal. However, the relationship between TL and common metabolic risk factors for CHD is not well understood. Whether these risk factors could explain pathways from TL to CHD warrants further attention. OBJECTIVE: To examine...

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Identifiers

PMID: 28515044
DOI: 10.1161/CIRCRESAHA.116.310517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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