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Article

Investigating the impact of metabolic syndrome traits on telomere length: a Mendelian randomization study

6 Jul 2023

Abstract excerpt

OBJECTIVE: Observational studies have reported bidirectional associations between metabolic syndrome (MetS) traits and short leukocyte telomere length (LTL), a TL marker in somatic tissues and a proposed risk factor for age-related degenerative diseases. However, in Mendelian randomization studies, longer LTL has been paradoxically associated with higher MetS risk. This study investigated the hypothesis that...

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Share to Birth, Development, and Health
Share to Epigenetics and DNA Methylation
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37415075
DOI: 10.1002/oby.23810

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