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Article

Insights Into Causal Effects of Genetically Proxied Lipids and Lipid-Modifying Drug Targets on Cardiometabolic Diseases.

Journal of the American Heart Association - 4 Feb 2025

Fu Liwan, Liu Qin, Cheng Hong, Zhao Xiaoyuan, Xiong Jingfan, Mi Jie

Abstract excerpt

BACKGROUND: The differential impact of serum lipids and their targets for lipid modification on cardiometabolic disease risk is debated. This study used Mendelian randomization to investigate the causal relationships and underlying mechanisms. METHODS: Genetic variants related to lipid profiles and targets for lipid modification were sourced from the Global Lipids Genetics Consortium. Summary data for 10...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39868518
DOI: 10.1161/JAHA.124.038857
PMCID: PMC12074789

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LPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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