Article
Exploring the causal pathway from omega-6 levels to coronary heart disease: A network Mendelian randomization study.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 10 Feb 2020
Liao Li-Zhen, Li Wei-Dong, Liu Ying, Li Jia-Ping, Zhuang Xiao-Dong, Liao Xin-Xue
Abstract excerpt
BACKGROUND AND AIMS: Evidence on the effect of omega-6 fats on coronary heart disease (CHD) risk remains inconclusive. We applied a network MR framework to determine the causal effects between omega-6 levels and CHD and the potential cholesterol metabolic risk factors (Total cholesterol, TC; Low-density lipoprotein cholesterol, LDL-C; High-density lipoprotein cholesterol, HDL-C; Triglycerides, TG) which might act...
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