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Article

Mendelian randomization to assess causal effects of blood lipids on coronary heart disease: lessons from the past and applications to the future.

Current opinion in endocrinology, diabetes, and obesity - 1 Apr 2016

Burgess Stephen, Harshfield Eric

Abstract excerpt

PURPOSE OF REVIEW: Mendelian randomization is a technique for judging the causal impact of a risk factor on an outcome from observational data using genetic variants. Although evidence from Mendelian randomization for the effects of major lipids and lipoproteins on coronary heart disease (CHD) risk has been around for a relatively long time, new data resources and new methodological approaches have given fresh...

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Identifiers

PMID: 26910273
DOI: 10.1097/MED.0000000000000230
PMCID: PMC4816855

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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