Article
The association between telomere length and blood lipids: a bidirectional two-sample Mendelian randomization study.
Frontiers in endocrinology - 1 Jan 2024
Yang Shengjie, Wang Xinyue, Li Yujuan, Zhou Lijun, Guo Gang, Wu Min
Abstract excerpt
Background: Observational studies suggest an association between telomere length (TL) and blood lipid (BL) levels. Nevertheless, the causal connections between these two traits remain unclear. We aimed to elucidate whether genetically predicted TL is associated with BL levels via Mendelian randomization (MR) and vice versa. Methods: We obtained genetic instruments associated with TL, triglycerides (TG),...
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