Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL18 Gene Variants Influence the Susceptibility to Chagas Disease.

PLoS neglected tropical diseases - 1 Mar 2016

Leon Rodriguez Daniel A, Carmona F David, Echeverría Luis Eduardo, González Clara Isabel, Martin Javier

Abstract excerpt

Chagas disease is a parasitic disorder caused by the infection with the flagellated protozoan Trypanosoma cruzi. According to the World Health Organization, more than six million people are currently infected in endemic regions. Genetic factors have been proposed to influence predisposition to infection and development of severe clinical phenotypes like chronic Chagas cardiomyopathy (CCC). Interleukin 18 (IL18)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Chagas Disease
Share to Colombia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genetic Variation

Share to Haplotypes

Share to Interleukin-18

Source

Open in PubMed Open full text

Identifiers

PMID: 27027876
DOI: 10.1371/journal.pntd.0004583
PMCID: PMC4814063

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL18 Gene Variants Influence the Susceptibility to Chagas Disease.PMID 27027876Read ↗

Association of IL18 genetic polymorphisms with Chagas disease in Latin American populations.Semantic proximity Read ↗

Functional IL18 polymorphism and susceptibility to Chronic Chagas Disease.Semantic proximity Read ↗

Investigation of the role of IL17A gene variants in Chagas disease.Semantic proximity Read ↗

A Specific IL6 Polymorphic Genotype Modulates the Risk of Trypanosoma cruzi Parasitemia While IL18, IL17A, and IL1B Variant Profiles and HIV Infection Protect Against Cardiomyopathy in Chagas Disease.Semantic proximity Read ↗

Genetic polymorphisms of IL17A associated with Chagas disease: results from a meta-analysis in Latin American populations.Semantic proximity Read ↗

Relationship between single nucleotide polymorphism of interleukin-18 and susceptibility to pulmonary tuberculosis in the Chinese Han population.Semantic proximity Read ↗

Lack of Association of IL6 polymorphism with the susceptibility to Chagas disease in Latin American populations.Semantic proximity Read ↗

Genetic Polymorphisms of Il-18 and Their Association with Infectious Diseases – An UpdateSemantic proximity Read ↗

Polymorphisms in the interleukin 18 receptor 1 gene and tuberculosis susceptibility among Chinese.Semantic proximity Read ↗

Polymorphisms in Genes Affecting Interferon-γ Production and Th1 T Cell Differentiation Are Associated With Progression to Chagas Disease Cardiomyopathy.Semantic proximity Read ↗

Genetic Polymorphisms of IL17 and Chagas Disease in the South and Southeast of Brazil.Semantic proximity Read ↗

Genetic Polymorphism at CCL5 Is Associated With Protection in Chagas' Heart Disease: Antagonistic Participation of CCR1+ and CCR5+ Cells in Chronic Chagasic Cardiomyopathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.