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Article

Association of IL18 genetic polymorphisms with Chagas disease in Latin American populations.

PLoS neglected tropical diseases - 1 Nov 2019

Strauss Mariana, Acosta-Herrera Marialbert, Alcaraz Alexia, Casares-Marfil Desiré, Bosch-Nicolau Pau, Lo Presti María Silvina, Molina Israel, González Clara Isabel, Martín Javier

Abstract excerpt

Host genetic factors have been suggested to play an important role in the susceptibility to Chagas disease. Given the influence of interleukin 18 (IL-18) in the development of the disease, in the present study, we analyzed three IL18 genetic variants (rs2043055, rs1946518, rs360719) regarding the predisposition to Trypanosoma cruzi infection and the development of chronic Chagas cardiomyopathy (CCC), in different...

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Identifiers

PMID: 31751351
DOI: 10.1371/journal.pntd.0007859
PMCID: PMC6894881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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