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Article

Investigation of the role of IL17A gene variants in Chagas disease.

Genes and immunity - 1 Dec 2015

Leon Rodriguez D A, Echeverría L E, González C I, Martin J

Abstract excerpt

Human host genetic factors have been suggested to be determinants of the prevalence and clinical forms of Chagas disease. In this regard, IL-17A is believed to control parasitemia and protect against heart disease. In this work, we assessed whether IL17A gene polymorphisms are related to infection and/or development of the cardiac form of Chagas disease by genotyping for five IL17A SNPs (rs4711998, rs8193036,...

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PMID: 26468780
DOI: 10.1038/gene.2015.42

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