Article
Genetic Susceptibility to Cardiac and Digestive Clinical Forms of Chronic Chagas Disease: Involvement of the CCR5 59029 A/G Polymorphism.
PloS one - 1 Jan 2015
de Oliveira Amanda Priscila, Bernardo Cássia Rubia, Camargo Ana Vitória da Silveira, Ronchi Luiz Sérgio, Borim Aldenis Albaneze, de Mattos Cinara Cássia Brandão, de Campos Júnior Eumildo, Castiglioni Lílian, Netinho João Gomes, Cavasini Carlos Eugênio, Bestetti Reinaldo Bulgarelli, de Mattos Luiz Carlos
Abstract excerpt
The clinical manifestations of chronic Chagas disease include the cardiac form of the disease and the digestive form. Not all the factors that act in the variable clinical course of this disease are known. This study investigated whether the CCR5Δ32 (rs333) and CCR5 59029 A/G (promoter region--rs1799987) polymorphisms of the CCR5 gene are associated with different clinical forms of chronic Chagas disease and with...
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