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Article

Genetic polymorphisms of IL17A associated with Chagas disease: results from a meta-analysis in Latin American populations.

Scientific reports - 19 Mar 2020

Strauss Mariana, Palma-Vega Miriam, Casares-Marfil Desiré, Bosch-Nicolau Pau, Lo Presti María Silvina, Molina Israel, González Clara Isabel, Martín Javier, Acosta-Herrera Marialbert

Abstract excerpt

Genetic factors and the immunologic response have been suggested to determine the susceptibility against the infection and the outcome of Chagas disease. In the present study, we analysed three IL17A genetic variants (rs4711998, rs8193036 and rs2275913) regarding the predisposition to Trypanosoma cruzi infection and the development of chronic Chagas cardiomyopathy (CCC) in different Latin American populations. A...

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Identifiers

PMID: 32193469
DOI: 10.1038/s41598-020-61965-5
PMCID: PMC7081280

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