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Article

Effects of common GRM5 genetic variants on cognition, hippocampal volume and mGluR5 protein levels in schizophrenia.

Brain imaging and behavior - 1 Apr 2018

Matosin Natalie, Newell Kelly Anne, Quidé Yann, Andrews Jessica Lee, Teroganova Nina, Green Melissa Jayne, Fernandez Francesca

Abstract excerpt

GRM5 (coding for metabotropic glutamate receptor 5, mGluR5) is a promising target for the treatment of cognitive deficits in schizophrenia, but there has been little investigation of its association with cognitive and brain phenotypes within this disorder. We examined the effects of common genetic variation in GRM5 with cognitive function, hippocampal volume, and hippocampal mGluR5 protein levels in schizophrenia...

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Source

Identifiers

PMID: 28405888
DOI: 10.1007/s11682-017-9712-0

Genes

GRM5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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