Polymorphisms in MIR137HG and microRNA-137-regulated genes influence gray matter structure in schizophrenia.

doi:10.1038/tp.2015.211

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Article

Polymorphisms in MIR137HG and microRNA-137-regulated genes influence gray matter structure in schizophrenia.

Translational psychiatry - 2 Feb 2016

Wright C, Gupta C N, Chen J, Patel V, Calhoun V D, Ehrlich S, Wang L, Bustillo J R, Perrone-Bizzozero N I, Turner J A

Abstract excerpt

Evidence suggests that microRNA-137 (miR-137) is involved in the genetic basis of schizophrenia. Risk variants within the miR-137 host gene (MIR137HG) influence structural and functional brain-imaging measures, and miR-137 itself is predicted to regulate hundreds of genes. We evaluated the influence of a MIR137HG risk variant (rs1625579) in combination with variants in miR-137-regulated genes TCF4, PTGS2, MAPK1...

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Identifiers

PMID: 26836412
DOI: 10.1038/tp.2015.211
PMCID: PMC4872419

Genes

MAPK1
MAPK3
PTGS2
TCF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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