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Article

The effect of a muscarinic receptor 1 gene variant on grey matter volume in schizophrenia.

Psychiatry research - 30 Nov 2015

Cropley Vanessa L, Scarr Elizabeth, Fornito Alex, Klauser Paul, Bousman Chad A, Scott Rodney, Cairns Murray J, Tooney Paul A, Pantelis Christos, Dean Brian

Abstract excerpt

Previous research has demonstrated that individuals with schizophrenia who are homozygous at the c.267C>A single nucleotide polymorphism (rs2067477) within the cholinergic muscarinic M1 receptor (CHRM1) perform less well on the Wisconsin Card Sorting Test (WCST) than those who are heterozygous. This study sought to determine whether variation in the rs2067477 genotype was associated with differential changes in...

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Source

Identifiers

PMID: 26481978
DOI: 10.1016/j.pscychresns.2015.09.004

Genes

CHRM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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