Article
Genome-wide association analysis with gray matter volume as a quantitative phenotype in first-episode treatment-naïve patients with schizophrenia.
PloS one - 1 Jan 2013
Wang Qiang, Xiang Bo, Deng Wei, Wu Junyao, Li Mingli, Ma Xiaohong, Wang Yingcheng, Jiang Lijun, McAlonan Grainne, Chua Siew E, Sham Pak C, Hu Xun, Li Tao
Abstract excerpt
Reduced Gray matter (GM) volume is a core feature of schizophrenia. Mapping genes that is associated with the heritable disease-related phenotypes may be conducive to elucidate the pathogenesis of schizophrenia. This study aims to identify the common genetic variants that underlie the deficits of GM volume in schizophrenia. High-resolution T1 images and whole genome genotyping data were obtained from 74...
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