Article
A polymorphism in the glutamate metabotropic receptor 7 is associated with cognitive deficits in the early phases of psychosis.
Schizophrenia research - 1 Nov 2022
Chaumette Boris, Sengupta Sarojini M, Lepage Martin, Malla Ashok, Iyer Srividya N, Kebir Oussama, Dion Patrick A, Rouleau Guy A, Krebs Marie-Odile, Shah Jai L, Joober Ridha
Abstract excerpt
Schizophrenia is an illness characterized by positive symptoms, negative symptoms, and cognitive impairments. Cognitive impairments occur before the onset of psychosis and could reflect glutamatergic dysregulation. Thus, identifying associations between genetic variations in genes coding for glutamatergic receptors and cognitive impairment in schizophrenia may help in understanding the basis of these deficits and...
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