Article
Histone peptide microarray screen of chromo and Tudor domains defines new histone lysine methylation interactions
14 Mar 2017
Abstract excerpt
BACKGROUND: Histone posttranslational modifications (PTMs) function to regulate chromatin structure and function in part through the recruitment of effector proteins that harbor specialized "reader" domains. Despite efforts to elucidate reader domain-PTM interactions, the influence of neighboring PTMs and the target specificity of many reader domains is still unclear. The aim of this study was to use a...
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