Article
mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome
2023-05-17
Abstract excerpt
<h4>ABSTRACT</h4> Bromodomains regulate gene expression by recognizing protein motifs containing acetyllysine. Although originally characterized as histone-binding proteins, it has since become clear that these domains interact with other acetylated proteins, perhaps most prominently transcription factors. The likely transient nature and low stoichiometry of such modifications, however, has made it challenging to...
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Identifiers and source
- Literature Corpus work
- 38beeddb-1259-54e8-ba5c-afaf3aa6d6da
- DOI
- 10.1101/2023.05.17.541126