Article

Orthogonal Proteomics Methods to Unravel the HOTAIR Interactome

2021-11-03

Abstract excerpt

Accumulating evidence highlights the role of long non-coding RNAs (lncRNA) in cellular homeostasis, and their dysregulation in disease settings. Most lncRNAs function by interacting with proteins or protein complexes. While several orthogonal methods have been developed to identify these proteins, each method has its inherent strengths and limitations. Here, we combine two RNA-centric methods ChIRP-MS and RNA-BioI...

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Literature Corpus work: 1c6ec6c3-5a17-51fd-a539-4cf6e984d58c
DOI: 10.21203/rs.3.rs-1008423/v1

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