Article

Nucleosome context regulates chromatin reader preference

2025-04-29

Abstract excerpt

<h4>ABSTRACT</h4> Chromatin is more than a simple genome packaging system, and instead locally distinguished by histone post-translational modifications (PTMs) that can directly change nucleosome structure and / or be “read” by chromatin-associated proteins to mediate downstream events. An accurate understanding of histone PTM binding preference is vital to explain normal function and pathogenesis, and has reveal...

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Literature Corpus work: 2540b5bf-71a1-54ce-803d-cf33e22a23d2
DOI: 10.1101/2025.04.29.651129

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