Article

The BRPF1 bromodomain is a molecular reader of di-acetyllysine

2020-02-13

Abstract excerpt

<h4>ABSTRACT</h4> Bromodomain-containing proteins are often part of chromatin-modifying complexes, and their activity can lead to altered expression of genes that drive cancer, inflammation and neurological disorders in humans. Bromodomain-PHD finger protein 1 (BRPF1) is part of the MOZ (monocytic leukemic zinc-finger protein) HAT (histone acetyltransferase) complex, which is associated with chromosomal transloca...

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Literature Corpus work: f224f369-c769-5693-8011-bea494d9f0ca
DOI: 10.1101/2020.02.13.948091

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