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Article

Quantifying intracellular rates of glycolytic and oxidative ATP production and consumption using extracellular flux measurements.

The Journal of biological chemistry - 28 Apr 2017

Mookerjee Shona A, Gerencser Akos A, Nicholls David G, Brand Martin D

Abstract excerpt

Partitioning of ATP generation between glycolysis and oxidative phosphorylation is central to cellular bioenergetics but cumbersome to measure. We describe here how rates of ATP generation by each pathway can be calculated from simultaneous measurements of extracellular acidification and oxygen consumption. We update theoretical maximum ATP yields by mitochondria and cells catabolizing different substrates....

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Identifiers

PMID: 28270511
DOI: 10.1074/jbc.M116.774471
PMCID: PMC5409486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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