Article

The Energetic Cost of Adrenergic Signaling in Primary Human Fibroblasts

2026-07-10

Abstract excerpt

Stress involves the activation of cellular, physiological, and emotional processes that cost energy—nothing is free in biology. In mammals, the stress response involves hormone release, including norepinephrine (NE), which increases energy expenditure. To quantify the energetic cost of NE signaling in a simple cellular system, we interrogated the dose (0 – 10 μM NE) and time-dependent (up to 10 hours) effects of a...

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Literature Corpus work: 8be0ab46-1eb7-5699-aa2f-1f119bca9d8a
DOI: 10.64898/2026.07.09.737569

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