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Genetically encoded tool for manipulation of ATP/ADP ratio in human cells

2025-08-15

Abstract excerpt

The ability of cells to power energy-demanding processes depends on maintaining the ATP hydrolysis reaction a billion-fold away from equilibrium. Cells respond to changes in energy state by sensing changes in ATP, ADP, AMP, and inorganic phosphate. A key barrier to a better understanding of the maintenance of energy homeostasis is a lack of tools for direct manipulation of energy state in living cells. Here, we re...

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Identifiers and source

Literature Corpus work
366eeada-95cb-54ea-8ec4-ee766121ac4d
DOI
10.1101/2025.08.12.670003
Open publication

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Genetically encoded tool for manipulation of ATP/ADP ratio in human cellsDOI 10.1101/2025.08.12.670003
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