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Article

Catabolic efficiency of aerobic glycolysis: the Warburg effect revisited.

BMC systems biology - 6 May 2010

Vazquez Alexei, Liu Jiangxia, Zhou Yi, Oltvai Zoltán N

Abstract excerpt

BACKGROUND: Cancer cells simultaneously exhibit glycolysis with lactate secretion and mitochondrial respiration even in the presence of oxygen, a phenomenon known as the Warburg effect. The maintenance of this mixed metabolic phenotype is seemingly counterintuitive given that aerobic glycolysis is far less efficient in terms of ATP yield per moles of glucose than mitochondrial respiration. RESULTS: Here, we...

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Identifiers

PMID: 20459610
DOI: 10.1186/1752-0509-4-58
PMCID: PMC2880972

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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