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Article

The role of single-nucleotide variants of the energy metabolism-linked genes SIRT3, PPARGC1A and APOE in amyotrophic lateral sclerosis risk.

Genes & genetic systems - 13 May 2017

Albani Diego, Pupillo Elisabetta, Bianchi Elisa, Chierchia Armando, Martines Rosalba, Forloni Gianluigi, Beghi Ettore

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a multifactorial disease, possibly with contributions from genetics and lifestyle. We examined variants in genes relevant to energy metabolism and physical activity in a case-control association study, with the aim of assessing genetics and physical activity as contributors to ALS risk. A well-characterized sample of Italian ALS patients (101) and controls (101) from the...

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Source

Identifiers

PMID: 28239025
DOI: 10.1266/ggs.16-00023

Genes

APOE
SIRT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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