Article

Polygenic Link Between Blood Lipids And Amyotrophic Lateral Sclerosis

2017-05-17

Abstract excerpt

Dyslipidemia is common among patients with amyotrophic lateral sclerosis (ALS). We aimed to test the association and causality between blood lipids and ALS, using polygenic analyses on the summary results of genome-wide association studies. Polygenic risk scores (PRS) based on low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC) risk alleles were significantly associated with a higher risk of ALS...

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Literature Corpus work: 23e0b4db-6ed4-5e99-8aa2-8074cf6234a5
DOI: 10.1101/138156

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