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Article

Lipids and amyotrophic lateral sclerosis: A two-sample Mendelian randomization study.

European journal of neurology - 1 Jul 2023

Xia Kailin, Klose Veronika, Högel Josef, Huang Tao, Zhang Linjing, Dorst Johannes, Fan Dongsheng, Ludolph Albert C

Abstract excerpt

OBJECTIVE: Previous observational studies revealed a potential but partially controversial relation between lipid metabolism and the risk of amyotrophic lateral sclerosis (ALS), potentially prone to bias. Therefore, we aimed to study whether lipid metabolism involves genetically determined risk factors for ALS through Mendelian randomization (MR) analysis. METHODS: Using genome-wide association study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36999624
DOI: 10.1111/ene.15810

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