Article

Physical exercise is a risk factor for amyotrophic lateral sclerosis: Convergent evidence from mendelian randomisation, transcriptomics and risk genotypes

2020-12-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Amyotrophic lateral sclerosis (ALS) is a universally fatal neurodegenerative disease. ALS is determined by gene-environment interactions and improved understanding of these interactions may lead to effective personalised medicine. The role of physical exercise in the development of ALS is currently controversial. <h4>Methods</h4> We dissected the exercise-ALS relationship in a...

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Literature Corpus work: dfbe23cc-258f-55be-92f1-f7b45de24d28
DOI: 10.1101/2020.11.24.20238063

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