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Article

A review of Mendelian randomization in amyotrophic lateral sclerosis

10 Nov 2021

Abstract excerpt

Amyotrophic lateral sclerosis is a relatively common and rapidly progressive neurodegenerative disease that, in the majority of cases, is thought to be determined by a complex gene-environment interaction. Exponential growth in the number of performed genome-wide association studies combined with the advent of Mendelian randomization is opening significant new opportunities to identify environmental exposures...

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PMID: 34791088
DOI: 10.1093/brain/awab420

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