Article

Do MTHFR C677T Genetic Polymorphism Influence in the Pathogenesis of Amyotrophic Lateral Sclerosis?

2021-10-01

Abstract excerpt

<title>Abstract</title> <p>Amyotrophic Lateral Sclerosis (ALS) is a progressive and lethal neurodegenerative disease without a definitive diagnostic test and effective treatment. A plethora of studies suggest that genetic factors play an important role in ALS development, and potentially link folate pathway dysregulation to disease pathogenesis. This study aims to evaluate folate dysregulation due to <italic>MTHF...

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Literature Corpus work: bf238e3d-0779-5f6b-a906-09abfeaf1ab4
DOI: 10.21203/rs.3.rs-939291/v1

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