Article
New multilocus linkage disequilibrium measure for tag SNP selection.
Journal of bioinformatics and computational biology - 1 Feb 2017
Liao Bo, Wang Xiangjun, Zhu Wen, Li Xiong, Cai Lijun, Chen Haowen
Abstract excerpt
Numerous approaches have been proposed for selecting an optimal tag single-nucleotide polymorphism (SNP) set. Most of these approaches are based on linkage disequilibrium (LD). Classical LD measures, such as D' and r2, are frequently used to quantify the relationship between two marker (pairwise) linkage disequilibria. Despite of their successful use in many applications, these measures cannot be used to measure...
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