Article
Discovering Genome-Wide Tag SNPs Based on the Mutual Information of the Variants.
PloS one - 1 Jan 2016
Elmas Abdulkadir, Ou Yang Tai-Hsien, Wang Xiaodong, Anastassiou Dimitris
Abstract excerpt
Exploring linkage disequilibrium (LD) patterns among the single nucleotide polymorphism (SNP) sites can improve the accuracy and cost-effectiveness of genomic association studies, whereby representative (tag) SNPs are identified to sufficiently represent the genomic diversity in populations. There has been considerable amount of effort in developing efficient algorithms to select tag SNPs from the growing...
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