Article
Tagging SNP-set selection with maximum information based on linkage disequilibrium structure in genome-wide association studies.
Bioinformatics (Oxford, England) - 15 Jul 2017
Wang Shudong, He Sicheng, Yuan Fayou, Zhu Xinjie
Abstract excerpt
MOTIVATION: Effective tagging single-nucleotide polymorphism (SNP)-set selection is crucial to SNP-set analysis in genome-wide association studies (GWAS). Most of the existing tagging SNP-set selection methods cannot make full use of the information hidden in common or rare variants associated diseases. It is noticed that some SNPs have overlapping genetic information owing to linkage disequilibrium (LD)...
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