Article
Informative SNPs selection based on two-locus and multilocus linkage disequilibrium: criteria of max-correlation and min-redundancy.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Li Xiong, Liao Bo, Cai Lijun, Cao Zhi, Zhu Wen
Abstract excerpt
Currently, there are lots of methods to select informative SNPs for haplotype reconstruction. However, there are still some challenges that render them ineffective for large data sets. First, some traditional methods belong to wrappers which are of high computational complexity. Second, some methods ignore linkage disequilibrium that it is hard to interpret selection results. In this study, we innovatively derive...
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