Article
A multilocus linkage disequilibrium measure based on mutual information theory and its applications.
Genetica - 1 Dec 2009
Zhang Lei, Liu Jianfeng, Deng Hong-Wen
Abstract excerpt
Evaluating the patterns of linkage disequilibrium (LD) is important for association mapping study as well as for studying the genomic architecture of human genome (e.g., haplotype block structures). Commonly used bi-allelic pairwise measures for assessing LD between two loci, such as r(2) and D', may not make full and efficient use of modern multilocus data. Though extended to multilocus scenarios, their...
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