Article
Evaluation of an algorithm of tagging SNPs selection by linkage disequilibrium.
Clinical biochemistry - 1 Mar 2006
Tang Nelson L S, Pharoah Paul D P, Ma Suk Ling, Easton Douglas F
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) are the most abundant kind of genetic polymorphism in the human genome. They are important in both genetic research and genetic testing in a clinical setting, such as in the area of pharmacogenetics. In order to improve efficiency, tagging SNPs (tagSNPs) are selected in genes of interest to represent other co-related SNPs in linkage disequilibrium (LD) with the...
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