Article
Genome-wide selection of tag SNPs using multiple-marker correlation.
Bioinformatics (Oxford, England) - 1 Dec 2007
Hao K
Abstract excerpt
MOTIVATIONS: The tag SNP approach is a valuable tool in whole genome association studies, and a variety of algorithms have been proposed to identify the optimal tag SNP set. Currently, most tag SNP selection is based on two-marker (pairwise) linkage disequilibrium (LD). Recent literature has shown that multiple-marker LD also contains useful information that can further increase the genetic coverage of the tag...
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