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A Hierarchical Clustering Method of Selecting Kernel SNP to Unify Informative SNP and Tag SNP.

IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000

Liao Bo, Li Xiong, Cai Lijun, Cao Zhi, Chen Haowen

Abstract excerpt

Various strategies can be used to select representative single nucleotide polymorphisms (SNPs) from a large number of SNPs, such as tag SNP for haplotype coverage and informative SNP for haplotype reconstruction, respectively. Representative SNPs are not only instrumental in reducing the cost of genotyping, but also serve an important function in narrowing the combinatorial space in epistasis analysis. The...

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PMID: 26357082
DOI: 10.1109/TCBB.2014.2351797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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