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Article

FastTagger: an efficient algorithm for genome-wide tag SNP selection using multi-marker linkage disequilibrium.

BMC bioinformatics - 29 Jan 2010

Liu Guimei, Wang Yue, Wong Limsoon

Abstract excerpt

BACKGROUND: Human genome contains millions of common single nucleotide polymorphisms (SNPs) and these SNPs play an important role in understanding the association between genetic variations and human diseases. Many SNPs show correlated genotypes, or linkage disequilibrium (LD), thus it is not necessary to genotype all SNPs for association study. Many algorithms have been developed to find a small subset of SNPs...

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Identifiers

PMID: 20113476
DOI: 10.1186/1471-2105-11-66
PMCID: PMC3098109

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