Article
MicroRNA-214 regulates smooth muscle cell differentiation from stem cells by targeting RNA-binding protein QKI.
Oncotarget - 21 Mar 2017
Wu Yutao, Li Zhoubin, Yang Mei, Dai Bing, Hu Feng, Yang Feng, Zhu Jianhua, Chen Ting, Zhang Li
Abstract excerpt
MicroRNA-214(miR-214) has been recently reported to regulate angiogenesis and embryonic stem cells (ESCs) differentiation. However, very little is known about its functional role in vascular smooth muscle cells (VSMCs) differentiation from ESCs. In the present study, we assessed the hypothesis that miR-214 and its target genes play an important role in VSMCs differentiation. Murine ESCs were seeded on...
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