Article
Role of specific microRNAs in regulation of vascular smooth muscle cell differentiation and the response to injury.
Journal of cardiovascular translational research - 1 Jun 2010
Song Zifang, Li Guohong
Abstract excerpt
Vascular smooth muscle cells (VSMCs) exhibit remarkable plasticity during postnatal development. Vascular injury initiates and perpetuates VSMCs dedifferentiation to a synthetic phenotype, which has been increasingly recognized to play a central role in neointimal hyperplasia during the pathogenesis of vascular proliferative diseases. MicroRNAs (miRNAs) are a novel class of regulatory noncoding RNAs that regulate...
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