Article
Defective smooth muscle development in qkI-deficient mice.
Development, growth & differentiation - 1 Jan 2000
Li Zhenghua, Takakura Nobuyuki, Oike Yuichi, Imanaka Takanobu, Araki Kimi, Suda Toshio, Kaname Tadashi, Kondo Tatsuya, Abe Kuniya, Yamamura Ken-Ichi
Abstract excerpt
The qkI gene encodes an RNA binding protein which was identified as a candidate for the classical neurologic mutation, qkv. Although qkI is involved in glial cell differentiation in mice, qkI homologues in other species play important roles in various developmental processes. Here, we show a novel function of qkI in smooth muscle cell differentiation during embryonic blood vessel formation. qkI null embryos died...
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